I like the top part on the lighter skyline; the logo and the strapline work well together I feel and, combined with the colours behind it, I do think that it all looks nice like that so I would keep those.
It's below that where I'm not so sure; I think the colours are good but as said, having so many fonts doesn't work. I can sense what you're trying to do by having so many but it just doesn't work, it feels a bit messy and, on top of that, it is actually hard to read which you don't want from a poster.
Beyond that, the 'contact us for a quote' line and then the details box below don't work either for me, I still find the contact us line quite hard to read too whilst the box surrounding the details feels too empty, the details don't really stand out.