If she works in a "lets make s**t pretty" industry, like design, then make that mo-fo damn pretty and let her personality shine through in the pictures and words. If she's a proper professional, its all about the formal, suit wearing stuff like how many different sizes of times she can use.
A couple of tips from my own experience:
• Keep to one page if possible (apparently multi page = ego)
• It needs to be designed to fit a portrait A4 (I was once told at interview that they'd spent 2 hours trying to print my landscape CV and even then they'd only got it landscape A5)
• DON'T put her picture on her CV. It was rated as one of the worst things a candidate can do, on one of these job site things.
• DON"T use a coloured background! (It really irritates bean counters when they have to print toner intensive CVs)
Of all my CV's incarnations over the years, my personal fave was a 4 page document that was really well designed and works perfectly both on screen and in print... Unfortunately, employers didnt share my vision and 4 landscape pages of charcoal grey, white and magenta were a happy medium for most office printers.