chrome on OSX is pretty poor nowadays - very bloated software, seems they're rushing to release updates everytime they think they have a great new idea.
it also tries to interrupt half the features Safari 6 introduced by redirecting them to chrome for web based tasks instead. pretty cheeky, but also really sh*ttily pulled off.
chrome and safari run on the same webkit engine, so there really isnt any speed difference between the two apps.
google chrome is good if most of your services are run by google. if not? stick with safari 6.